How to make pills
In recent years, drug safety issues have attracted much attention, and the method of making pills has also become one of the hot topics. This article will combine the hot content on the Internet in the past 10 days to introduce the pill production process, relevant data and precautions in detail to help readers have a more comprehensive understanding of this field.
1. Basic process of tablet production
The production of tablets is a complex and rigorous process that usually includes the following steps:
| step | content |
|---|---|
| 1. Raw material preparation | Choose active ingredients and excipients that meet standards, such as fillers, adhesives, lubricants, etc. |
| 2. Mix | Mix the ingredients evenly in proportion to ensure a consistent distribution of ingredients in the tablet. |
| 3. Granulation | The mixed powder is granulated by wet granulation or dry granulation. |
| 4. Tablet pressing | Use a tablet press to compress the granules into tablets, controlling weight and hardness. |
| 5. Coating | Some tablets require coating to improve taste or control release rate. |
| 6. Packaging | Pack the finished tablets and label them with production date, expiration date and other information. |
2. Key data for tablet production
Here are the key data to look at during the tablet making process:
| parameter | Standard range | illustrate |
|---|---|---|
| Raw material purity | ≥99% | Ensure high purity of active ingredients and excipients. |
| Mixing uniformity | RSD≤5% | The mixed powder needs to be evenly distributed. |
| Tablet hardness | 4-8kg/cm² | If the hardness is too low, it will be brittle; if it is too high, it will be difficult to dissolve. |
| Tablet weight | ±5% tolerance | The weight of each tablet needs to be controlled within the standard range. |
3. Things to note when making tablets
1.Raw material selection: Raw materials that comply with pharmacopoeia standards must be used to avoid insufficient efficacy or side effects due to quality problems.
2.environmental control: The production workshop must be kept clean, with temperature and humidity controlled within specified ranges to prevent contamination.
3.Equipment maintenance: Regularly inspect and maintain equipment such as tablet presses to ensure trouble-free production.
4.Quality inspection: Each batch of tablets needs to undergo content measurement, dissolution testing, etc. to ensure compliance with standards.
4. Recent hot topics and hot content
In the past 10 days, hot topics about pill production have mainly focused on the following aspects:
| topic | heat index | Main content |
|---|---|---|
| Risks of Homemade Pills | 85 | Discuss possible safety hazards associated with home-prepared pills. |
| Progress in 3D printing pills | 78 | Introducing the application prospects of 3D printing technology in tablet production. |
| Modern production of traditional Chinese medicine tablets | 72 | Explore how to combine traditional Chinese medicine with modern pharmaceutical technology. |
5. Summary
The production of tablets is a technology-intensive process, involving raw material selection, mixing, tableting, coating and other aspects. Every step needs to be strictly controlled to ensure the safety and effectiveness of the medicine. Recently, the risks of home-made pills and the progress of 3D printed pills have become hot topics, reflecting the public's high concern about drug safety and technological innovation. I hope that through the introduction of this article, readers can have a deeper understanding of the pill making method.
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